The Broken Hill Aboriginal Land Council is open to uranium exploration in New South Wales' far west.
However BHALC chair Maureen O’Donnell said the details and risks still need to be discussed before any mining begins.
"I've got to see what benefits (it has) for the people," she told the ABC.
"I don't like uranium as it is because it causes a lot of cancer and there's enough sickness but it sort of depends on how they're going to do it and what they're going to do."
The New South Wales state government lifted the ban on uranium exploration earlier this year in a bid to ramp up the state’s involvement in the mining boom.
"It is time for NSW to look at every opportunity to join the mining boom, which is delivering enormous profits and jobs to Western Australia, Queensland and South Australia," NSW premier Barry O'Farrell said at the time.
The far west of New South Wales is thought to be rich in uranium, exploration applications close next week.